Research Article
Antibacterial and Antioxidant Activities of Cochlospermum planchonii Hook Leaves and White Tips of Agama agama Feces of Korhogo (Côte d’Ivoire)
Kouakou Yeboue Koffi Francois*,
Kouame Yao Yves,
Miezan Bile Aka Patrice,
Sene Mbaye,
Tia Vama Etienne,
Yapi Houphouet Felix
Issue:
Volume 11, Issue 4, December 2025
Pages:
113-121
Received:
30 October 2025
Accepted:
17 November 2025
Published:
20 December 2025
DOI:
10.11648/j.jdmp.20251104.11
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Abstract: The aim of this study was to evaluate the antibacterial and antioxidant properties of three samples from aqueous extracts of Cochlospermum planchonii leaves and the white tips of Agama agama feces. The phytochemical analyses were carried out by HPLC and spectrophotometric assays. The antioxidant activity was carried out by the DPPH method. As for antibacterial activity, it consisted of determining the inhibition percentage by solid disk diffusion. The Minimum Inhibitory Concentration (MIC) was then determined using the liquid dilution method in sterile test tubes. The phenolic profiles reveal the presence of twelve (12) phenolic compounds identified in the 3 samples E1, E2 and E3. All these phenolic compound showed a significant difference (p ≤ 0.05) when compared with each other. The best antioxidant activity was obtained with sample E2 (80.81 ± 1.36%) compared to vitamin C (59.7 ± 5.11%) used as a reference molecule. Sample E1 gave the best antibacterial activity against the pathogenic strains Stahylococcus aureus (ATCC29213) and Pseudomonas aeruginosa (ATCC27853) with respective MICs of 250 mg/mL and 200 mg/mL. This better efficacy of sample E1 was confirmed by maximum inhibition zones of 14 mm against Pseudomonas aeruginosa and 12 mm against Staphylococcus aureus at the concentration of 500 mg/mL, corresponding to 15.55% and 13% inhibition respectively. This study showed a therapeutic potential of Cochlospermum planchonii and white tips of Agama agama feces as a source of natural antimicrobial and antioxidant agents.
Abstract: The aim of this study was to evaluate the antibacterial and antioxidant properties of three samples from aqueous extracts of Cochlospermum planchonii leaves and the white tips of Agama agama feces. The phytochemical analyses were carried out by HPLC and spectrophotometric assays. The antioxidant activity was carried out by the DPPH method. As for a...
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